This chapter provides an overview of the US Regulatory framework applicable to standardization. It discusses the US law and policy instruments codified in the NTTAA and the OMB Circular, as well as the procedural requirements for American national consensus standards introduced by the ANSI. Similar to the previous chapter on the EU, this chapter covers the value of private voluntary standards in US policies and legislation based on the judgments of the US courts. Likewise, it also discusses whether and when standards development organizations may breach the US antitrust provisions, in particular Sections 1 and 2 of the Sherman Act and the SDOAA.