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Chapter 15 - Final Reflections on the Neuro-behavioral Manifestations of Prader-Willi Syndrome

Published online by Cambridge University Press:  26 May 2022

By
Deepan Singh
Edited by
Deepan Singh
Deepan Singh
Affiliation:
Maimonides Medical Center in Brooklyn
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Summary

This chapter summarizes the content of the book and puts it in the context of neuroscience and the current understanding of human behavior as it applies to PWS. The concept of response monitoring and its dysfunction leading to response perseveration is reviewed. In addition, impulsivity and obsessive-compulsive symptoms and their relationship to response monitoring is reiterated. Concerns are raised in relation to the currently utilized treatments against behavioral problems in PWS, which happen to be antidepressants. The need to map the neuronal connections that are functioning abnormally in PWS is emphasized. Caregiver burden is a significant problem in PWS and the need for more resources such as the development of centers of excellence for the treatment of PWS is reviewed.

Keywords

conclusionresponse monitoringbehavioral problemspsychopharmacologytherapycaregiverimpulsivityreflection
Type
Chapter
Information
Neuro-behavioral Manifestations of Prader-Willi Syndrome
A Guide for Clinicians and Caregivers
 , pp. 171 - 175
Publisher: Cambridge University Press
Print publication year: 2022

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References

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