Transverse myelitis is an inflammation of the spinal cord that commonly presents with acute to subacute bilateral motor weakness and sensation changes below the level of the spinal cord lesion, as well as anal and urinary sphincter control impairment. The causes of transverse myelitis can be viral, bacterial, parasitic, rheumatological/antibody-mediated, vascular, paraneoplastic, demyelinating, or idiopathic. Idiopathic transverse myelitis is typically a monophasic illness. Most cases of transverse myelitis are related to an underlying autoimmune condition like multiple sclerosis, neuromyelitis optica spectrum disorder (NMOSD), or myelin oligodendrocyte glycoprotein (MOG)-associated disorder.