Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-27T20:22:16.914Z Has data issue: false hasContentIssue false

Chapter 26 - Multiple Sclerosis in Pregnancy

from Section 4 - Neurological Disorders in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Alexa Eberle ,
Meena Khandelwal  and
Amira El-Messidi
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
Get access

Summary

A 34-year-old G2P1 with long-standing multiple sclerosis (MS) is referred by her neurologist for prenatal care of a spontaneous pregnancy at 10 weeks’ gestation by dating sonography. She takes prenatal vitamins and has no obstetric complaints.

Keywords

Multiple sclerosisMaternal-fetal risksAntepartum, intrapartum, postpartum managementExacerbation, postpartumDisease-modifying drugsInterferon beta/glatiramer acetateNatalizumabCounselingBreastmilk, storage
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 361 - 369
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Readings

Bove, R, Alwan, S, Friedman, JM, et al. Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review. Obstet Gynecol. 2014;124(6):1157–1168.CrossRefGoogle ScholarPubMed
Coyle, PK, Oh, J, Magyari, M, et al. Management strategies for female patients of reproductive potential with multiple sclerosis: an evidence-based review. Mult Scler Relat Disord. 2019; 32:54–63.CrossRefGoogle ScholarPubMed
Dobson, R, Dassan, P, Roberts, M, et al. UK consensus on pregnancy in multiple sclerosis: ‘Association of British Neurologists’ guidelines. Pract Neurol. 2019;19(2):106–114.CrossRefGoogle ScholarPubMed
Fang, X, Patel, C, Gudesblatt, M. Multiple sclerosis: clinical updates in women’s health care primary and preventive care review. Obstet Gynecol. 2020;135(3):757–758.Google Scholar
Kalinowska, A, Kułakowska, A, Adamczyk-Sowa, M, et al. Recommendations for neurological, obstetrical and gynaecological care in women with multiple sclerosis: a statement by a working group convened by the Section of Multiple Sclerosis and Neuroimmunology of the Polish Neurological Society. Neurol Neurochir Pol. 2020;54(2):125–137.Google Scholar
Liguori, NF, Alonso, R, Pinheiro, AA, et al. Consensus recommendations for family planning and pregnancy in multiple sclerosis in Argentina. Mult Scler Relat Disord. 2020; 43:102147.CrossRefGoogle ScholarPubMed
Pozzilli, C, Pugliatti, M, ParadigMS Group. An overview of pregnancy-related issues in patients with multiple sclerosis. Eur J Neurol. 2015;22 Suppl 2:34–39.CrossRefGoogle ScholarPubMed
Thöne, J, Thiel, S, Gold, R, et al. Treatment of multiple sclerosis during pregnancy – safety considerations. Expert Opin Drug Saf. 2017;16(5):523–534.CrossRefGoogle ScholarPubMed
Toscano, M, Thornburg, LL. Neurological diseases in pregnancy. Curr Opin Obstet Gynecol. 2019;31(2):97–109.CrossRefGoogle ScholarPubMed
Varytė, G, Zakarevičienė, J, Ramašauskaitė, D, et al. Pregnancy and multiple sclerosis: an update on the disease modifying treatment strategy and a review of pregnancy’s impact on disease activity. Medicina (Kaunas). 2020;56(2):49. Published 2020 Jan 21.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×