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Chapter 17 - Preimplantation Genetic Testing (PGT)

from Section 3 - Genetics and Preimplantation Genetic Testing

Published online by Cambridge University Press:  05 March 2021

By
Eliezer Girsh  and
Mira Malcov
Edited by
Eliezer Girsh
Eliezer Girsh
Affiliation:
Barzilai Medical Center, Ashkelon
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Summary

The risk for transmission of genetic disorders to offspring has been a critical obstacle for couples known to be carriers for severe genetic disorders. To prevent the birth of an affected child, prenatal testing by amniocentesis or chorionic villus sampling (CVS) is offered. An alternative approach, available with assisted reproductive technology (ART), is preimplantation genetic testing – PGT – enabling testing of the embryo for the familial disorder before the corresponding embryo is transferred to the uterus of the mother.

Type
Chapter
Information
A Textbook of Clinical Embryology , pp. 207 - 225
Publisher: Cambridge University Press
Print publication year: 2021

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