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Effect of propylene glycol supplementation around parturition on milk yield, reproduction performance and some hormonal and metabolic characteristics in dairy cows

Published online by Cambridge University Press:  01 June 2009

Andrea Formigoni ,
Marie-Christine Cornil ,
Alberto Prandi ,
Archimede Mordenti ,
Andriana Rossi ,
Daniel Portetelle  and
Robert Renaville
Andrea Formigoni
Affiliation:
Facoltà di Medicina Veterinaria, Istituto di Zootecnia e Nutrizione Animate, Università degli Studi di Bologna, I-40064 Ozzano Emilia (Bologna), Italia
Marie-Christine Cornil
Affiliation:
Département de Biologie Moléculaire et de Physiologie Animate, Faculté des Sciences Agronomiques, Avenue Maréchal Juin 13, B-5030 Gembloux, Belgique
Alberto Prandi
Affiliation:
Dipartimento di Scienze degli Alimenti, Università degli Studi di Undine, I-33010 Pagnacco (Undine), Italia
Archimede Mordenti
Affiliation:
Facoltà di Medicina Veterinaria, Istituto di Zootecnia e Nutrizione Animate, Università degli Studi di Bologna, I-40064 Ozzano Emilia (Bologna), Italia
Andriana Rossi
Affiliation:
Dipartimento di Scienze degli Alimenti, Università degli Studi di Undine, I-33010 Pagnacco (Undine), Italia
Daniel Portetelle
Affiliation:
Département de Microbiologie, Faculté des Sciences Agronomiques, Avenue Maréchal Juin 6, B-5030 Gembloux, Belgique
Robert Renaville
Affiliation:
Département de Biologie Moléculaire et de Physiologie Animate, Faculté des Sciences Agronomiques, Avenue Maréchal Juin 13, B-5030 Gembloux, Belgique
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Summary

Thirty-nine multiparous Holstein cows were used to measure the effect of propylene glycol treatment around parturition on milk yield, reproductive efficiency and some hormone and metabolite concentrations. Cows were assigned randomly to control (n = 19) or propylene glycol treated (n = 20) groups. Propylene glycol (300g) was administered directly mixed with the diet from day 10 prior to the expected calving date until parturition (day 0) and orally after dilution in 1 l water on days 3, 6, 9 and 12. Blood samples were collected on days −20, −5, 0, 3, 10, 25 and 50 while milk samples were taken weekly until 13 weeks post partum. Body condition scores, recorded on days −20, 15 and 50, were not affected by propylene glycol administration. Propylene glycol did not significantly affect milk yield or composition but linear somatic cell score measured from the first 13 weeks post partum was reduced by propylene glycol administration (P < 0·01). Moreover, propylene glycol reduced milk urea (−25 mg/l, P < 0·05), especially during the first 9 weeks post partum. Plasma insulin concentrations were similar in both groups during the experiment while insulin-like growth factor I (P < 0·05) and insulin-like growth factor-binding protein 3 (P < 0·001) levels were higher on days 10, 25 and 50 post partum in the propylene glycol group. Propylene glycol administration decreased plasma non-esterified fatty acid concentrations (P < 0·05 to P < 0·01) but increased total cholesterol levels (P < 0·01) after parturition while 3-hydroxy-butyrate levels were unaffected by the treatment. Changes in the hormone and metabolic concentrations after propylene glycol administration in the last few days of gestation and the first week of lactation seem to indicate that energy balance in the treated group was probably more positive than in the control group. There was also evidence that propylene glycol administration prevented fatty liver syndrome and hastened the resumption of oestrous cycles (P < 0·001).

Type
Original Articles
Information
Journal of Dairy Research , Volume 63 , Issue 1 , February 1996 , pp. 11 - 24
Copyright
Copyright © Proprietors of Journal of Dairy Research 1996

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References

REFERENCES

Baxter, R. C. & Martin, J. L. 1989 Binding proteins for insulin-like growth factors: structure, regulation and function. Progress in Growth Factor Research 1 49–68CrossRefGoogle Scholar
Bertics, S. J., Grummer, R. R., Cadorniga-Valino, C. & Stoddahd, E. E. 1992 Effect of prepartum dry matter intake on liver triglyceride concentration and early lactation. Journal of Dairy Science 75 1914–1922Google Scholar
Breibr, B. H., Gluckman, P. D. & Bass, J. J. 1988 The somatotroph axis in young steers: influence of nutritional status and oestradiol-17β on hepatic high- and low-affinity somatotrophic binding sites. Journal of Endocrinology 116 169–177Google Scholar
Butler, W. R. & Smith, R. D. 1989 Interrelationships between energy balance and postpartum reproductive function in dairy cattle. Journal of Dairy Science 72 767–783CrossRefGoogle ScholarPubMed
Carroll, D. J., Grummer, R. R. & Mao, F. C. 1992 Progesterone production by cultured luteal cells in the presence of bovine low- and high-density lipoproteins purified by heparin affinity chromatography. Journal of Animal Science 70 2516–2526CrossRefGoogle ScholarPubMed
Chiesa, F., Gaiani, R., Formigoni, A. & Accorsi, P. A. 1991 Hormone and metabolic variations in high-yielding dairy cows during dry period and lactation. Archivio Veterinaria Italiana 42 157–169Google Scholar
Chilliard, Y. 1993 [Metabolic adaptation and partition of nutrients in the lactating animal.] In Biologic de la Lactation, pp. 431–475. Paris: INRAGoogle Scholar
Cohick, W. S., McGuirb, M. A., Clemmons, D. R. & Bauman, D. E. 1992 Regulation of insulin-like growth factor-binding proteins in serum and lymph of lactating cows by somatotropin. Endocrinology 130 1508–1514Google ScholarPubMed
Edmonson, A. J., Lean, I. J., Weaver, L. D., Farver, T. & Webster, G. 1989 A body condition scoring chart for Holstein dairy cows. Journal of Dairy Science 72 68–78CrossRefGoogle Scholar
Emery, R. S., Burg, N., Brown, L. D. & Blank, G. N. 1964 Detection, occurrence, and prophylactic treatment of borderline ketosis with propylene glycol feeding. Journal of Dairy Science 47 1074–1079Google Scholar
Fronk, T. J., Schultz, L. H. & Hardie, A. R. 1980 Effect of dry period overconditioning on subsequent metabolic disorders and performance of dairy cows. Journal of Dairy Science 63 1080–1091CrossRefGoogle Scholar
Goering, H. K. & Van Soest, P. J. 1970 Forage Fiber Analysis. Bethesda, MD: Agricultural Research Service (USDA Agriculture Handbook no. 379)Google Scholar
Gröhn, Y., Lindberg, L. -A., Bruss, M. L. & Farver, T. B. 1983 Fatty infiltration of liver in spontaneously ketotic dairy cows. Journal of Dairy Science 66 2320–2328CrossRefGoogle ScholarPubMed
Grummer, R. R. 1993 Etiology of lipid-related metabolic disorders in periparturient dairy cows. Journal of Dairy Science 76 3882–3896Google Scholar
Harrison, L. M. & Randel, R. D. 1986 Influence of insulin and energy intake on ovulation rate, luteinizing hormone and progesterone in beef heifers. Journal of Animal Science 63 1228–1235CrossRefGoogle ScholarPubMed
Hintz, R. L. 1987 Somatomedin C/insulin-like growth factor I receptors on human mononuclear cells and the IM-9 lymphoid cell line. Methods in Enzymology 146 234–239CrossRefGoogle ScholarPubMed
Ingalls, W. G., Convey, E. M. & Haes, H. D. 1973 Bovine serum LH, GH, and prolactin during late pregnancy, parturition and early lactation. Proceedings of the Society for Experimental Biology and Medicine 143 161–164Google Scholar
Lemal, D., Renaville, R., Claes, V., Ruelle, L., Fabry, J., Burny, A., Underwood, L. E. & Ketelslegers, J. -M. 1989 Effect of pituitary somatotropin injections on plasma insulin-like growth factor-I and somatotropin profiles in growing heifers. Journal of Animal Science 67 2715–2723CrossRefGoogle ScholarPubMed
Lucy, M. C., Beck, J., Staples, C. R., Head, H. H., De La Sota, R. L. & Thatcher, W. W. 1992 Follicular dynamics, plasma metabolites, hormones and insulin-like growth factor I (IGF-I) in lactating cows with positive or negative energy balance during the preovulatory period. Reproduction, Nutrition, Development 32 331–342CrossRefGoogle ScholarPubMed
McGuire, M. A., Bauman, D. E., Miller, M. A. & Hartnell, G. F. 1992 Response of somatomedins (IGF-I and IGF-II) in lactating cows to variations in dietary energy and protein and treatment with recombinant n-methionyl bovine somatotropin. Journal of Nutrition 122 128–136Google Scholar
Martillotti, F., Antongiovanni, M., Rizzi, L., Santi, E. & Bittante, G. 1987 [Methods of analysis for the estimation of the nutritive value of livestock feeds.] Roma: IPRA, CNR (Quaderni melodologici no. 8)Google Scholar
Merrill, W. G. & Galton, A. M. 1985 Winter dairy management school. (Cornell University Monographs no. 84, p. 84)Google Scholar
Oltner, R. & Wiktorsson, H. 1983 Urea concentrations in milk and blood as influenced by feeding varying amounts of protein and energy to dairy cows. Livestock Production Science 10 457–467Google Scholar
Prandi, A., Cojiin, A., Gabai, G., Rossi, C. & Bono, G. 1992 [Plasma variations of some hormones and nutrients associated with energy metabolism in high yielding Italian Simmental cows.] Archivia Veterinaria Italiana 43 213–221Google Scholar
Prandi, A., Motta, M., Tondolo, A. & Rossi, C. 1994 Evaluation of the reproductive efficiency of Simmental and Fricsian dairy cows farmed in Friuli (Northeast Italy) by the analysis of progesterone levels. Theriogenology 42 65–78Google Scholar
Reid, I. M., Rowlands, G. J., Dew, A. M., Collins, R. A., Roberts, C. J. & Manston, R. 1983 The relationship between post-parturient fatty liver and blood composition in dairy cows. Journal of Agricultural Science 101 473–481Google Scholar
Rémesy, C., Chilliard, Y., Rayssiguier, Y., Mazur, A. & Demigné, C. 1986 [Hepatic metabolism of carbohydrates and lipids in ruminants: principal interactions in pregnane and lactation.] Reproduction, Nutrition, Développement 26 205–226Google Scholar
Renaville, R., Devolder, A., Massart, S., Sneyers, M., Burny, A. & Portetelle, D. 1993 Changes in the hypophyseal-gonadal axis during the onset of puberty in young bulls. Journal of Reproduction and Fertility 99 443–449Google Scholar
Ronge, H., Blum, J., Clement, C., Jans, F., Leuenberger, H. & Binder, H. 1988 Somatomedin C in dairy cows related to energy and protein supply and to milk production. Animal Production 47 165–183Google Scholar
Ropstad, K., Vik-Mo, L. & Refsdal, A. O. 1989 Levels of milk urea, plasma constituents and rumen liquid ammonia in relation to the feeding of dairy cows during early lactation. Acta Veterinaria Scandinavia 30 199–208CrossRefGoogle Scholar
SAS 1991 User's Guide: Statistics, v. 6. Cary, NC: SAS InstituteGoogle Scholar
Saueh, F. D., Erfle, J. D. & Fisher, L. J. 1973 Propylene glycol and glycerol as a feed additive for lactating dairy cows: an evaluation of blood metabolite parameters. Canadian Journal of Animal Science 53 265–271Google Scholar
Sharma, B. K., Vandehaar, M. J. & Ames, N. K. 1994 Expression of insulin-like growth factor-I in cows at different stages of lactation and in late lactation cows treated with somatotropin. Journal of Dairy Science 77 2232–2241CrossRefGoogle ScholarPubMed
Short, R. E., Bellows, R. A., Staigmiller, R. B., Berakdinelli, J. G. & Custer, E. E. 1990 Physiological mechanisms controlling anestrus and infertility in postpartum beef cattle. Journal of Animal Science 68 799–816CrossRefGoogle ScholarPubMed
Simmons, C. R., Bergen, W. G., Vandehaar, M. J., Sprecher, D. J., Sniffen, C. J., Stanisiewski, E. P. & Tucker, H. A. 1994 Protein and fat metabolism in cows given Somavubove before parturition. Journal of Dairy Science 77 1835–1847Google Scholar
Skaar, T. C., Grummer, R. R., Dentine, M. R. & Stauffacher, R. H. 1989 Seasonal effects of propartum and postpartum fat and niacin feeding on lactation performance and lipid metabolism. Journal of Dairy Science 72 2028–2038CrossRefGoogle ScholarPubMed
Spicer, L. J., Alpizar, E. & Echternkamp, S. E. 1993 Effects of insulin, insulin-like growth factor I, and gonadotropins on bovine granulosa cell proliferation, progesterone production, estradiol production, and(or) insulin-like growth factor I production in vitro. Journal of Animal Science 71 1232–1241Google Scholar
Spicer, L. J. & Enright, W. J. 1991 Concentrations of insulin-like growth factor I and steroids in follicular fluid of preovulatory bovine ovarian follicles. Effect of daily injections of a growth hormone-releasing factor analog and(or) thyrotropin-releasing hormone. Journal of Animal Science 69 1133–1139Google Scholar
Spicer, L. J., Tucker, W. B. & Adams, G. D. 1990 Insulin-like growth factor-I in dairy cows: relationships among energy balance, body condition, ovarian activity, and estrous behaviour. Journal of Dairy Science 73 929–937CrossRefGoogle Scholar
Studer, V. A., Grummer, R. R., Bertics, S. J. & Reynolds, C. K. 1993 Effect of prepartum propylene glycol administration on periparturient fatty liver in dairy cows. Journal of Dairy Science 76 2931–2939CrossRefGoogle ScholarPubMed
Vazquez-Añon, M., Bertics, S., Luck, M., Grummer, R. R. & Pinheiro, J. 1994 Peripartum liver triglyceride and plasma metabolites in dairy cows. Journal of Dairy Science 77 1521–1528CrossRefGoogle ScholarPubMed
Veenhuizen, J. J., Drackley, J. K., Richard, M. J., Sanderson, T. P., Miller, L. D. & Young, J. W. 1991 Metabolic changes in blood and liver during development and early treatment of experimental fatty liver and ketosis in cows. Journal of Dairy Science 74 4238–4253Google Scholar
Vega, J. R., Gibson, C. A., Skaak, T. C., Hadsell, D. L. & Baumrucker, C. R. 1991 Insulin-like growth factor (IGF)-I and (IGF)-II and IGF binding proteins in serum and mammary secretions during the dry period and early lactation in dairy cows. Journal of Animal Science 69 2538–2547CrossRefGoogle Scholar
Vicini, J. L., Buonomo, F. C., Veenhuizen, J. J., Miller, M. A., Clemmons, D. R. & Collier, R. J. 1991 Nutrient balance and stage of lactation affect responses of insulin, insulin-like growth factor-I and -II and insulin-like growth factor-binding protein-2 to somatotropin administration in dairy cows. Journal of Nutrition 121 1656–1664Google Scholar
Weller, J. I., Saran, A. & Zeliger, Y. 1992 Genetic and environmental relationships among somatic cell count, bacterial infection, and clinical mastitis. Journal of Dairy Science 75 2532–2540CrossRefGoogle ScholarPubMed
Zapf, J., Hauri, C., Waldvogel, M., Futo, E., Häsler, H., Binz, K., Guler, H. P., Schmid, C. & Froesch, E. R. 1989 Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophyseetomized and diabetic rats. Proceedings of the National Academy of Sciences, USA 86 3813–3817Google Scholar