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2 - Malaria: the real killer

Published online by Cambridge University Press:  24 November 2009

Gerald Esch
Affiliation:
Wake Forest University, North Carolina
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Summary

Open your mouth: this will shake your shaking …

If all the wine in my bottle will recover him, I will help his ague.

The Tempest, William Shakespeare (1564–1616)

Since I have never had malaria, all I know about rigor, or the high fever that follows, is what I read from those who have had the experience. Not long ago, in preparing to write this essay, I spent some time interviewing Robert Desowitz, the American parasitologist who has so marvelously written about his many experiences working with tropical diseases over the years, e.g., The Malaria Capers, Who Gave Pinta to the Santa Maria, etc. I asked Bob if, while living so long in so many exotic parts of the world, he had ever come down with malaria, or any of the other tropical diseases about which he had written so much or done so much research. He said that he had not been infected with anything except Plasmodium vivax and Plasmodium falciparum, that both of them came at the same time, and by accident! Acquiring malaria by accident is ironic in his case because he had spent nine years at the West African Trypanosome Research Lab in Jos, in the northern part of Nigeria, working on trypanosomes in the employ of the British Colonial Service. He then spent five more years as Chairman of the Department of Parasitology at the University of Singapore, plus several more years in southeastern Asia while with the U.S. Army at their SEATO (Southeast Asia Treaty Organization) lab in Bangkok, Thailand.

Type
Chapter
Information
Parasites and Infectious Disease
Discovery by Serendipity and Otherwise
, pp. 128 - 149
Publisher: Cambridge University Press
Print publication year: 2007

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References

Carson, R. 1962. Silent Spring. New York: Houghton Mifflin.Google Scholar
Desowitz, R. S. 1991. The Malaria Capers. New York: Norton.Google Scholar
Desowitz, R. S. 1997. Who Gave Pinta to the Santa Maria? New York: Norton.Google Scholar
Escalante, A. A. and Ayala, F. J.. 1994. Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences. Proceedings of the National Academy of Sciences USA 91: 11373–11377.CrossRefGoogle ScholarPubMed
Perkins, S. L. and Schall, J. J.. 2002. A molecular phylogeny of malarial parasites recovered from cytochrome b sequences. Journal of Parasitology 88: 972–978.CrossRefGoogle Scholar
Rich, S. H. and Ayala, F. J.. 2003. Progress in malaria research: the case for phylogenies. Advances in Parasitology 54: 255–280.CrossRefGoogle Scholar
Roberts, F., Johnson, J. J., Kyle, D. E.et al. 1998. Evidence for a shikimate pathway in apicomplexan parasites. Nature 393: 801–805.CrossRefGoogle ScholarPubMed
Russell, P. 1955. Man's Mastery of Malaria. Oxford: Oxford University Press.Google Scholar
Storer, T. I. and Usinger, R. L.. 1957. General Zoology. New York: McGraw-Hill.Google Scholar
Waters, A. P., Higgins, D. G., and McCutchan, T. F.. 1991. Plasmodium falciparum appears to have arisen as the result of lateral transfer between avian and human hosts. Proceedings of the National Academy of Sciences USA 88: 3140–3144.CrossRefGoogle ScholarPubMed

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  • Malaria: the real killer
  • Gerald Esch, Wake Forest University, North Carolina
  • Book: Parasites and Infectious Disease
  • Online publication: 24 November 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511619021.004
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  • Malaria: the real killer
  • Gerald Esch, Wake Forest University, North Carolina
  • Book: Parasites and Infectious Disease
  • Online publication: 24 November 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511619021.004
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Malaria: the real killer
  • Gerald Esch, Wake Forest University, North Carolina
  • Book: Parasites and Infectious Disease
  • Online publication: 24 November 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511619021.004
Available formats
×