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5 - Overview of radiation therapy

Published online by Cambridge University Press:  05 March 2012

Jeremy Price
Affiliation:
The Canberra Hospital, Canberra, Australia
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Summary

Radiation therapy after breast conservation

Following breast-conserving surgery, whole breast irradiation aims to reduce the risk of local recurrence by dealing with any possible residual DCIS, and it may also deal effectively with additional small invasive foci. However, the use of RT is not considered to be any substitute for obtaining pathologically clear margins. Frequently a “boost” is given to the tumor bed during whole breast irradiation.

RT for invasive cancer after BCT

While surgery followed by RT is currently standard treatment for most cases of invasive cancer, RT may be omitted for some favorable lesions (small grade 1, ER-positive, node-negative tumors with complete excision) particularly when these arise in older women (age > 70 years). In such selected cases, the risk of recurrence is probably not more than ~5% at 10 years even without RT. Tamoxifen and/or an aromatase inhibitor are usually then employed.

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Publisher: Cambridge University Press
Print publication year: 2011

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