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Case 74 - Amyloidosis of the larynx and pharynx

Published online by Cambridge University Press:  19 November 2019

By
Nina Zidar ,
Katarina Dimnik  and
Aleš Grošelj
Edited by
Alessandro Franchi
Alessandro Franchi
Affiliation:
Università degli Studi di Firenze, Italy
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Summary

A 49-year-old otherwise healthy woman noticed a painless swelling of the pharyngeal mucosa. On examination, thickened, pale mucosa was found in the oropharynx (Figure 1A) and in the posterior part of the larynx between arytenoids (Figure 1B). Incisional biopsy was performed. Following the biopsy diagnosis, clinical examination was performed which did not reveal evidence of a systemic disease.

Type
Chapter
Information
Pearls and Pitfalls in Head and Neck Pathology , pp. 152 - 154
Publisher: Cambridge University Press
Print publication year: 2019

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References

Phillips, NM, Matthews, E, Altmann, C, Agnew, J, Burns, H. Laryngeal amyloidosis: diagnosis, pathophysiology and management. J Laryngol Otol. 2017;131:S41–S47.CrossRefGoogle ScholarPubMed
Rudy, SF, Jeffery, CC, Damrose, EJ. Clinical characteristics of laryngeal versus nonlaryngeal amyloidosis. Laryngoscope. 2018;128:670–674.CrossRefGoogle ScholarPubMed
Schönland, SO, Hegenbart, U, Bochtler, T, Mangatter, A, Hansberg, M, Ho, AD, et al. Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients. Blood. 2012;119:488–493.CrossRefGoogle ScholarPubMed
Mahmood, S, Bridoux, F, Venner, CP, Sachchithanantham, S, Gilbertson, JA, Rowczenio, D, et al. Natural history and outcomes in localised immunoglobulin light-chain amyloidosis: a long-term observational study. Lancet Haematol. 2015;2(6):e241–e250.CrossRefGoogle ScholarPubMed
Kourelis, TV, Kyle, RA, Dingli, D, Buadi, FK, Kumar, SK, Gertz, MA, et al. Presentation and outcomes of localized immunoglobulin light chain amyloidosis: the Mayo clinic experience. Mayo Clin Proc. 2017;92:908–917.CrossRefGoogle ScholarPubMed
Wierzbicka, M, Budzyński, D, Piwowarczyk, K, Bartochowska, A, Marszałek, A, Szyfter, W. How to deal with laryngeal amyloidosis? Experience based on 16 cases. Amyloid. 2012;19:177–181.CrossRefGoogle Scholar
Hazenberg, AJ, Hazenberg, BP, Dikkers, FG. Long-term follow-up after surgery in localized laryngeal amyloidosis. Eur Arch Otorhinolaryngol. 2016;273:2613–2620.CrossRefGoogle ScholarPubMed

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